Diflucan Side Effects. Severity: Major. You should check with your doctor immediately if any of these side effects occur when taking fluconazole:
- Abdominal or stomach pain
- chills
- clay-colored stools
- cough
- dark urine
- diarrhea
- difficulty with swallowing
- dizziness
- fast heartbeat
- fever
- general feeling of tiredness or weakness
- headache