Niacin Side Effects, Before Taking, Hot to Use & More

Niacin (vitamin B3) is a prescribed vitamin supplement; it is a water-soluble vitamin meaning the body can’t retain it, it is used for maintaining healthy cholesterol levels in the body and to some extent eliminating bad cholesterol from the body. Niacin replenishes patients who’re deficient in B3 and fights off pellagra; also lowers the risk of heart disease and treats coronary artery disease. Niacin is present in the form of quick/delayed release tablets ranging in dosages 500 mg, 750mg, and 1000 mg; the capsules are available in 125mg.



 Side Effects

If you experience the below mentioned adverse effects, then contact your doctor without delay.

  1. Niacin can contribute to symptoms such as dizziness, warmth, tingly skin, or redness, chills, sweating, itching under the skin, muscle pain, leg cramps, and insomnia.
  2. Niacin can also induce cold-like symptoms including the runny or stuffy nose, sore throat, coughing, sneezing, and fever.
  3. Severe side-effects include nausea and vomiting, skin flushing combined with dizziness, uneven or fast-pounding heartbeat, and shortness of breath. Rush to the emergency room ASAP.
  4. Other serious negative effects are gray colored stools, skin itching or rash, severe stomach pain, nausea, and vomiting, dark colored urine, and skin and eyes turn yellow. Report them to your doctor.
  5. Allergic reactions can also occur symptoms are skin rashes and itching, swollen tongue, lips, throat, sore throat, and hives. Get medical help immediately if these symptoms are manifested in you.


 How to Use?

Take vitamin B3 (niacin) supplements as per your doctor’s order and do not tamper with the dosage. Take the oral tablet with a glass of cold water; usually, it is preferred to consume before going to sleep and is also accompanied by Advil or aspirin is taken 30 minutes prior to niacin for avoiding flushing. Do not crush, chew or break the tablets that’ll significantly increase the release of dosage that the body won’t be able to handle.


How does it work?

Vitamin B3 (niacin) is a vital vitamin that is essential for cellular metabolism and the proper break-down of lipids, and carbohydrates. Its functioning is mainly such that its presence is crucial to produce two important chemicals, i.e., NAD and NADP. These chemicals then carry out metabolic operations in the cells and play a part in various bodily chemical reactions. A body deficient in B3 can’t properly carry out these functions.


Precautions (Before Taking)


Studies have indicated that Niacin supplements can have damaging effects on the fetus, so usage of this drug during pregnancy is highly discouraged. Only a certified health expert can comment on whether this supplement is worth the risk or not, so follow strict orders from your doctor in this situation.


Niacin does dissolve into breastmilk this may prove harmful for the nursing infant; again, the best course of action here is to consult with your medical health provider and then contemplate using niacin.

Medical History

It is of utmost importance that your doctor is informed about your medical history so, she/he is better aware and equipped to treat you with Niacin. If you have diabetes, liver or kidney problems, gallbladder problems, heart conditions such as angina, gout, or stomach ulcers then, you’re at risk of deadly or injurious interactions with niacin.

Allergy Information

Most people are susceptible to allergic reactions because of their sensitivity to allergens; so, your doctor needs to know if you’ve had any severe reactions to vitamins and supplements in the past or if you’re currently allergic to Niacin. This preventive measure is essential for health safety as allergic reactions can sometimes prove fatal.


Niacin should be avoided by patients who suffer from the severe liver disease, a stomach ulcer, or bleeding as interactions could prove fatal. Medications such as colestipol or Locholest, Prevalite, and Questran should not be taken in combination with Niacim; if you’re taking them then do so at least 4 to 6 hours before taking niacin.