Invokana (Canagliflozin) Side Effects, Important Info, Before Taking & More

Invokana, also called Canagliflozin, is an oral diabetes medicine that is used to treat high and low blood sugar levels. Invokana helps your kidneys reduce the level of glucose in the blood, improving blood sugar levels in people who have type 2 diabetes mellitus. It should be taken with diet and exercise to be effective.


Invokana also helps to prevent nerve problems, kidney damage, sexual function problems, and blindness. Furthermore, it reduces the risk of a heart attack and a stroke. However, it should not be used to treat type 1 diabetes.


Side effects

Invokana can treat type 2 diabetes, but it also has some side effects. Most of these side effects are minor and disappear as your body adjusts to the use of Invokana. However, seek immediate medical help if any of these side effects persist or worsen.

Minor side effects

  • Urinating more than usual
  • Dizziness
  • Genital infections
  • Lightheadedness
  • An unusually dry mouth

However, some of these side effects are severe and can become life-threatening if not treated immediately. Visit your doctor immediately if you experience any of the following side effects.


Major side effects

  • Feeling like you might faint
  • Burning or pain while urinating
  • Infections and swelling in your feet or legs
  • Ulcers
  • Any new pain or tenderness
  • Any signs of a genital infection including itching, odor, pain, swelling, burning, redness, or discharge
  • Any symptoms of ketoacidosis including stomach pain, nausea, confusion, unusual drowsiness, trouble breathing, or vomiting.
  • Dehydration
  • Little or no urination
  • Shortness of breath
  • Any signs of an allergic reaction including dizziness, itching, rash, and swelling.


How to use

Take Invokana orally, once a day, usually before breakfast unless instructed otherwise by your doctor. Invokana should be taken regularly to be effective. Your doctor may change your dosage according to your medical condition so make sure you follow the prescribed dosage closely. Invokana needs to be taken with an adequate diet plan, exercise regimen, special medical care, weight control, and regular blood sugar tests as part of a complete treatment program. Store Invokana in a cool, dry place.



  • Do not take Invokana if you are allergic to any of the active or inactive ingredients found in this medicine. It is advisable to ask for a list of ingredients from your pharmacist to avoid a severe allergic reaction.
  • As the side effects of Invokana include dizziness, drowsiness, and blurred vision, avoid operating any machinery or driving until you are sure about the way Invokana affects your body.
  • Make sure your doctor is aware of your medical history, especially if you have had mineral imbalances, kidney disease, low blood pressure, genital infections, dehydration, and heart failure.
  • Avoid drinking any alcoholic beverages as alcohol increases the risk of developing a high ketone level and low blood sugar.
  • Inform your doctor and dentist of all the medications you are taking before undergoing any surgery.


  • Use Invokana with caution in older adults as they are more sensitive to its side effects, especially dehydration, bone loss, dizziness, and fainting.
  • It is uncertain whether Invokana can harm an unborn baby and should only be taken if absolutely necessary. Consult your doctor about the use of Invokana if you are pregnant.
  • Pregnancy can also worsen or cause diabetes. Your doctor will need to monitor your blood sugar if you are pregnant and may even change your diabetes treatment.
  • It is uncertain whether Invokana can pass into breast milk and harm a nursing infant. Discuss the risks and benefits of taking Invokana with your doctor before breastfeeding.
  • Invokana should not be given to anyone under 18 years of age.