Diflucan (Fluconazole) Side Effects, Usefull Information, Before Taking & How to Take

Diflucan is an externally administered medicine that contains fluconazole as its primary ingredient. It is an antifungal medicine.

Diflucan is used for the treatment of vaginal, esophageal, and oral infections mainly caused by Candida – a type of yeast. It is also prescribed for treating fungal infections infested in people due to a weak immune system; mainly resulting from cancer treatment, transplant of bone marrow or acquired immunodeficiency syndrome (AIDS).


It may also be used for other purposes not mentioned in the guide.


Side effects of Diflucan

Diflucan, like all medicines, has some side effects. These range from mild to severe and should be reported to the doctor.

Some of the common side effects that are mild in nature are as follows:

  • Stomach upsets and pain
  • Diarrhea
  • Headache
  • Dizziness

Most of these side effects tend to occur at the start of the treatment and perish within a day or two as it does not take long for the body to adjust and get accustomed to the presence of the medicine. However, they may persist and start to worsen, triggering serious medical conditions. Therefore, seek medical help promptly if any side effect is experienced.


Some of the potential side effects it may cause include:

  • Fluttering in your chest
  • Breathlessness
  • Extreme dizziness
  • Fever accompanied by chills and body aches
  • Easy bruising or bleeding
  • Unusual weakness
  • Seizure, i.e., convulsions
  • Skin lesions
  • Signs of liver disorder, e.g., loss of appetite, stomach pain (upper right side), dark urine, clay-colored stools, etc.
  • Jaundice
  • Signs of an allergic reaction

Note that other side effects not listed in this guide may also be experienced. Usually, doctors and/or pharmacists inform the patients about the side effects they are likely to experience at the start of their treatment.

For further queries regarding this, you may consult your doctor and/or pharmacist.


How to use?

Before starting Diflucan, you are strongly advised to read out the directions on the prescription label and follow them carefully.

The medicine is administered orally. Usually, it is prescribed to be used once a day. However, if your doctor directs you otherwise, then follow your doctor’s instructions as the dosage varies, depending on your medical state. Take timely and balanced doses; neither skip nor overdose on Diflucan. If using the liquid form, make sure to use a special container to measure out the exact amount. You may take Diflucan with or without food.



  • Neither prescribe nor use it without a doctor’s recommendation.
  • It may interact negatively with a few medications including cisapride, erythromycin, and pimozide. Thus, give a list of all the medicines, if any, to your doctor as a safety measure.
  • It is not the best choice for people with certain disorders such as liver disease, kidney disease, and AIDS. Therefore, give your medical history to your doctor to avoid any inconvenience.


  • Do not use if allergic to Fluconazole
  • Do not use it during pregnancy as it may harm the baby.
  • Do not breastfeed a baby while using this medicine.
  • Keep it away from children’s reach, heat, and moisture.