Celebrex (Celecoxib) Side Effects, Important Information, Before Taking & More

Celebrex, also known as Celecoxib, is a nonsteroidal anti-inflammatory drug that is used to treat menstrual discomfort and pain, acute pain, and arthritis. It is available in the form of tablets and capsules. Celebrex limits the production of prostaglandins by blocking the enzymes that make it.


Decreasing the level of prostaglandins helps relieve pain and swelling, allowing you to carry out your daily activities comfortably. Celebrex is also used to cure hereditary polyps in the colon as well as juvenile rheumatoid arthritis in children who are over two years of age.


Side effects

Celebrex can treat arthritis and can help relieve pain, but it also has some side effects. Most of the side effects are common and disappear as your body adjusts to the use of Celebrex. However, visit your doctor immediately if any of these side effects worsen or persist.

Minor side effects

  • Dizziness
  • Nausea
  • Indigestion
  • Stomach pain
  • Sneezing, stuffy nose, or a sore throat
  • Insomnia
  • Gas
  • Rash
  • Swelling in the hands and feet
  • Diarrhea


However, some of the side effects are severe and can cause death if not treated immediately. Seek immediate medical help if you experience any of the major side effects.

Major side effects

  • Shortness of breath
  • Symptoms of stomach bleeding, including vomit resembling coffee grounds, bloody stools, and coughing up blood.
  • Rapid weight gain
  • Symptoms of anemia, including light-headedness, trouble concentrating, pale skin, and rapid heartbeat.
  • Signs of liver disease including loss of appetite, clay-colored stools, dark urine, and jaundice.
  • Symptoms of kidney disease including tiredness, swelling, and difficulty urinating.
  • Signs of an allergic reaction including swelling, trouble breathing, swollen lymph nodes, fever, itching, and dizziness.
  • Symptoms of a skin reaction including blistering, swelling in the tongue and face, sore throat, skin pain, and fever.


How to use?

Take Celebrex only according to the prescribed dosage, without increasing or decreasing your dosage. It is advisable to take Celebrex once or twice every day unless prescribed otherwise by your doctor. You can take Celebrex with food if you feel nauseous. If you cannot swallow the entire capsule, you can open it and sprinkle the contents into a spoon of applesauce. Make sure you swallow immediately without chewing. You can also refrigerate the mixture but make sure you drink it within six hours. Celebrex will not work immediately, and you have to take it regularly for at least two weeks to treat conditions like arthritis. Store Celebrex in a cool, dry place.



  • Do not use Celebrex if you are allergic to any of the active or inactive ingredients found in it, or to other NSAIDs, COX-2 inhibitors, and aspirin. It is advisable to ask for a list of ingredients from your pharmacist to avoid an allergic reaction
  • Inform your doctor of all the diseases you have had, especially if you have a history of stomach or esophagus problems, ulcers, blood disorders, high blood pressure, heart disease, liver disease, stroke, asthma, and nasal polyps.


  • Avoid drinking any alcoholic beverages and smoking while taking Celebrex, as they can increase the risk of stomach bleeding.
  • Inform your doctor and dentist of all the medications you are taking before undergoing any surgery.
  • Use Celebrex with caution in older adults as they are more sensitive to its side effects, especially kidney problems and stomach bleeding.


  • Celebrex can have harmful effects on an unborn baby and can affect normal labor and delivery if taken during the first and last trimesters. Consult your doctor about the safe use of Celebrex if you are pregnant or plan to become pregnant.
  • Celebrex can pass into breast milk, but it is uncertain whether it can harm a nursing infant. Consult your doctor about the use of Celebrex before breastfeeding.