Baclofen Side Effects, How it Works, Upsides & Downsides

Baclofen is available both as an oral and an injectable medicine that works to relax the skeletal muscles that are responsible for the movement of the body. Baclofen is related to the gamma-aminobutyric acid commonly known as GABA. This is naturally present in the brain as a neurotransmitter. Neurotransmitters are the chemicals that are used to send messages to the other nerve.


When GABA is released in the brain, it retards the activity of some nerves in the brain. Baclofen also works like GABA and blocks the working of nerves within the brain that are responsible for the contraction and relaxation of the muscles.


Side effects of taking Baclofen

While there are benefits, there are some side effects of taking Baclofen too. However, they differ in intensity and severity. Therefore, they are classified as minor and major side effects.


Minor side effects

Minor side effects are less severe and are curable in a short time if treated with proper care. The minor side effects of Baclofen are listed below:

  • Complain of dizziness is common
  • Dryness of the mouth
  • Face the problems related to low blood pressure
  • Vomiting and nausea are common
  • Weakness is reported
  • You experience seizures
  • You experience sexual disinterest
  • You feel drowsy
  • You feel excited
  • You get confused easily
  • You suffer from severe and frequent headaches
  • You suffer from insomnia


Major side effects

Major side effects are those that require medical assistance as soon as possible. Otherwise, they create serious problems that are difficult to cure. The major side effects of Bactrim are:

  • Face trouble breathing
  • You suffer from severe chest pain


How to take baclofen?

Take Baclofen orally as prescribed by your doctor. To avoid any confusions, read the prescription label to clear out all doubts. Do not ever increase or decrease your dose without consulting your doctor.

Do not stop taking the medicine at once as it can harm the body and result in seizures. Keep all medicines at room temperature away from direct heat, light, and moisture.



Some precautions you must take when using Baclofen include:

You should avoid taking Baclofen if you are allergic to any of its ingredients

It is better to inform your doctor before starting the medication if you suffer from any of the following medical conditions:

  • If you are on a narcotic (opioid) medication
  • You face sudden mood changes
  • You have an ulcer
  • You have experienced a stroke or blood clot
  • You have had epilepsy or other seizure disorder
  • You suffer from a kidney disease
  • You suffer from arthritis
  • You suffer from Parkinson’s disease

Avoid taking Baclofen during pregnancy as it can cause harm to the unborn baby. Talk to your doctor if you are pregnant or become pregnant while using Baclofen.

Discuss with your doctor whether you should take Baclofen if you are breastfeeding a baby as it can pass into breast milk.

Baclofen is also known to cause an ovarian cyst. Discuss with your doctor about this condition too.