Tylenol Side Effects, How to Take, What to Avoid & More

Tylenol is the known trade name for Acetaminophen and is popularly prescribed for relieving pain and reducing fever. It is used to treat headaches, muscle aches, cases of arthritis, colds and menstrual pains.


The active ingredient in this medicine is Acetaminophen alongside inactive ingredients such as diphenhydramine and methocarbamol. It is usually available over-the-counter and may have numerous other uses not mentioned in this medication guide.



Tylenol, like any medicinal drug, has some side effects which can be expected as your body adjusts to the new drugs in the system. A few of the common side effects which you are most likely to experience are listed below. Inform your doctor if they continue over a prolonged period and become severe:

  • Nausea
  • Vomiting
  • Constipation
  • Abdominal pain
  • Dyspepsia
  • Anemia
  • Pruritus
  • Wheezing
  • Diarrhea
  • Coughing
  • Hyperglycemia
  • Dizziness
  • Muscle spasms
  • Insomnia
  • Fatigue
  • Hypotension

Severe Side Effects:

If you go through any of the following or they become increasingly stringent, see your doctor immediately:

  • Severe upper stomach pain
  • Loss of appetite
  • Dark urine
  • Clay-colored stools
  • Yellowing of the skin or eyes
  • Trouble speaking and walking
  • Yellowing of eyes and/or skin
  • Peripheral edema
  • Tachycardia
  • Allergic reaction symptoms such as rash, dizziness
  • Hypoxia
  • Severe anxiety
  • Severe dizziness and difficulty breathing



Tylenol must be taken orally, with or without food. It is strongly instructed that you follow the dosage that your doctor prescribes; considering your medical conditions, age, weight and therapeutic response. Usually, it is directed that you take it once in the morning. If you use the concentrated solution, use the medicine dropper provided and not a household spoon.

If you are giving Tylenol to your child, make sure you know their weight to provide them with the right dose. Rapidly dissolving tablets are available which can be chewed or dissolved on the tongue. Caution is necessary when you use tablets; you must not chew or crush them, or split them. Swallow them whole.

Pain medications such as Tylenol work best when taken as soon as the symptoms of pain start to appear. If you wait until the pain such as your headache to spread and worsen, the medicine will not work as effectively.

It is to be noted that this medication isn’t for an extended usage, which is why it must not be taken for more than three days of your fever unless explicitly instructed by your doctor.



Before you start your prescribed dosage, inform your doctor about your medical history, specifically highlight any condition or history of certain muscle diseases, lung diseases, and substance abuse. You must discuss with your doctor if you have any of the following medical conditions:

  • Heart diseases such as congestive heart failure, angina, etc.
  • Breathing problems such as COPD, sleep apnea
  • Diabetes
  • Phenylketonuria (PKU)
  • Liver or kidney diseases
  • Glaucoma

It is also cautioned that Tylenol may cause liver damage, even if you take recommended dosages, and obviously risks increase at higher doses. The chances of liver complications increase substantially more if you regularly drink alcohol.

It is also instructed that you inform your doctor if you are taking any medicines beforehand, prescribed or not in nature and herbal drugs. According to which, your doctor will give you the precise prescription and dosage that suits your medical condition.



Elder individuals are prone to be more sensitive to the above-mentioned side effects, specifically dizziness and low blood pressure. They feel exceptionally dizzy when getting up from a lying or sitting position.

Tylenol may also interact with other medications such as Warfarin and can induce a hypersensitive reaction from your immune system. Inform your doctor about any such tendency.

This medicine is not recommended in the case of pregnancy; it is advised that Tylenol only is taken if extremely necessary; this drug is also known to pass into breast milk and cause undesirable effects. Consult your doctor about the risks and benefits.