Omeprazole Side Effects, Upsides, Downsides, Tips

Omeprazole is a drug belonging to a group of medications called proton pump inhibitors (PPIs). This medication is used to treat stomach and esophagus issues such as ulcers and acid reflux, etc. What this drug does it is that it decreases the amount of acid that your stomach is producing and also heals any damage that may have been caused by the acid to your stomach or esophagus.


It also prevents ulcers and prevents cancer of the esophagus as well. This medication also helps in relieving other symptoms which include heartburn, persistent coughs, and difficulty in swallowing. Omeprazole is also available over the counter; however, make to consult your doctor before taking any medication.

Side effects of this drug

Like any other medicine, Omeprazole too has its fair share of adverse effects. However, remember that if your doctor has prescribed you this medication, it is probably because the benefits outweigh the side effects. The severe side effects associated with this medication are rare, and most of the people do not experience them. Here is a list of some of the side effects that are associated with Omeprazole.

Minor side effects

Some minor side effects of this drug include:

  • Headaches
  • Abdominal pain
  • Gas
  • Diarrhea
  • Nausea
  • Vomiting


Major side effects

Some rare, yet more severe side effects of this drug include:

  • Low magnesium blood level
  • Irregular heartbeat
  • Signs of lupus
  • Clostridium difficile
  • Vitamin B-12 deficiency
  • A rash
  • Joint pain
  • Unusual pain in your wrist, thigh, hip or your back
  • Seizures
  • Kidney problems


How to use this medication?

Before taking this medication, make sure to follow all the directions given to you by your doctor. You will take this medication orally at least one hour before your meal, on a daily basis. The dosage will depend on your condition and how well you react to the treatment. Do not use this medication for a prolonged period, neither increase the dosage unless your doctor has told you to do so. Do not chew, crush or break the tablets. Instead, swallow the entire tablet with a glass filled with water. If you’re taking the liquid form, then make sure to use a measuring spoon to get the exact dose of the medicine.

Antacids can be taken with this drug; however, if you’re taking sucralfate, then make sure to take Omeprazole at least 30 minutes before. For patients who are self-treating, make sure not to use this medication for more than 14 days.




There are some things that you should know about before you take this medication. To ensure your safety and health, you must inform your doctor of all the medical conditions you have. Here are some of the conditions you need to let your doctor know about:

  • Allergies
  • Medical history of lupus
  • Medical history liver disease
  • Heartburn
  • Lightheadedness
  • Dizziness
  • Sweating
  • Jaw, chest, arm or shoulder pain
  • Unexplained weight loss
  • Heartburn
  • Trouble in swallowing
  • Bloody vomit
  • Vomit that looks like coffee grounds
  • Bloody or black stool frequent chest pain
  • Nausea
  • Vomiting
  • Abdominal pain

Using this medication may increase your risk of getting bone fractures, especially in adults.

Before you undergo surgery, make sure to inform your doctor about all the prescribed medications you’re taking.

Pregnant women and nursing mothers should not use this medication as it can harm their babies.